The global lipids genetics consortium glgc

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August undefined, 2024

WebUsing GWAS and comorbidity data, we present a network-based approach to predict candidate genes for lipid and lipoprotein traits. We apply a prediction pipeline … Web8 Dec 2024 · Studying people of diverse ancestries could also improve genetic research studies into many other diseases, the researchers suggest. Largest study to date The …

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http://lipidgenetics.org/ Web20 Dec 2024 · Furthermore, the results were similar in sensitivity analyses of genetic scores from variants strictly selected on the basis of the CHARGE and GLGC Consortium data (Table S6). Directionally consistent and significant results were similarly obtained for the individual end points including coronary artery disease, peripheral artery disease, aortic … hang yoga swing from chain high tree branch

Additive Effects of Genetic Interleukin‐6 Signaling Downregulation …

Web14 Dec 2016 · 2 University College London Genetics Institute, Department of Genetics, Environment and Evolution, London, United Kingdom. PMID: 27973560 PMCID: … WebThe Global Lipids Genetics Consortium (GLGC) is a world-wide collaboration of investigators dedicated to understanding the genetic etiology of quantitative lipid traits. … Web9 Dec 2024 · The study was led by the Global Lipids Genetics Consortium (GLGC), an international collaboration of scientists investigating the genetic etiology of quantitative … hang yong choi san francisco

The Causal Relationship Between Blood Lipids and …

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Web22 Apr 2024 · Variants were robustly associated with LDL-C in a meta-analysis of genome-wide association studies (GWAS) involving 188,578 individuals primarily (96%) of … WebGenetics; combined total 66 842 cases), stroke from METASTROKE (12 389 ischemic stroke cases), type 2 diabetes mellitus from DIAGRAM (Diabetes Genetics Replication and Meta-analysis; 34 840 cases), and lipids from GLGC (Global Lipids Genetic Consortium; 213 500 participants) consortia. Primary outcomes were CHD, type 2 diabetes hangyo ice cream near meWebGenome-wide association studies (GWASs) have implicated ∼380 genetic loci for plasma lipid regulation. However, these loci only explain 17–27% of the trait variance, and a … hangyo ice creams pvt ltd mangalore

"WebThe Global Lipids Genetics Consortium is a worldwide collaboration of investigators dedicated to understanding the genetic etiology of quantitative lipid traits 1 follower … " - The global lipids genetics consortium glgc

The global lipids genetics consortium glgc

A Mendelian randomization study of the effects of blood lipids on ...

Web15 Nov 2024 · We added two new data analyses using the GWAS summary statistics for four blood lipid traits from the Global Lipids Genetics Consortium (GLGC) and two traits from … Web1 Apr 2024 · After a rigorous evaluation of the quality of studies, the single-nucleotide polymorphisms (SNPs) associated with the four blood lipids were selected from the Global Lipids Genetic...

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Web13 Apr 2024 · After a rigorous evaluation of the quality of studies, the single-nucleotide polymorphisms (SNPs) associated with the four blood lipids were selected from the … http://csg.sph.umich.edu/willer/public/glgc-lipids2024/

http://lipidgenetics.org/ Web8 Dec 2024 · Studying people of diverse ancestries could also improve genetic research studies into many other diseases, the researchers suggest. Largest study to date. The …

Web15 Jul 2024 · Using a global lipidomic analysis, another landmark study identified 12,13-dihydroxy-9Z-octadecenoic acid ... For the fasting lipid traits, we used the findings of the Global Lipids Genetics Consortium (GLGC; based on N of up to 94,595) . As outcome data, we used summary statistics of genome wide association study ... Web15 May 2024 · We processed the Global Lipids Genetics Consortium (GLGC) GWAS study for four plasma lipids (HDL, LDL, TC, and TG, as listed in Table 2B ). These correlated …

Web4 Apr 2024 · Associations with CRC risk per one standard deviation increase in the genetically predicted lipids level were generated using inverse-variance weighted random …

Web29 Mar 2024 · 2Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai New York, United States 3Medical Scientist Training Program, Icahn School … hang young north cantonWebWe identify and annotate 157 loci associated with lipid levels at P < 5 × 10(-8), including 62 loci not previously associated with lipid levels in humans. Using dense genotyping in … hangyo ice creams private limitedWeb29 Mar 2024 · Shown are the multivariable MR (MVMR) results from the discovery analysis, using genetic instruments for plasma TG levels from Global Lipids Genetics Consortium (GLGC) and disease traits from UKB. Levels of statistical significance are categorized into three tiers: Tier 1 (BB): At least Bonferroni-significant in both the discovery (p<1.92 × 10 … hang your hat on idiomWeb11 Mar 2024 · Genetic association estimates for LDL-c were obtained from a meta-analysis of genome-wide association studies (GWAS) conducted by the Global Lipids Genetics Consortium (GLGC). 19 The meta-analysis was restricted to participants of European ancestry, and most contributing cohorts measured blood lipid levels after 8 or more hours … hang your glass couponWebTerms and conditions apply. Discovery drug target MR estimates on CHD. Analyses were performed using genetic associations with LDL-C, HDL-C, and TG from the Global Lipid … hang your hat grand haven miWebGLGC Global lipids genetics consortium GWAS Genome-wide associations studies IVW Inverse variance weighted MAGIC Meta-analyses of glucose and insulin-related traits consortium MR Mendelian randomisation Electronic supplementary material The online version of this article hang your hat homes ohioWeb6 Oct 2013 · Human genetic studies of lipid levels can identify targets for new therapies for cholesterol management and the prevention of heart disease and can complement … hang your glass adhesive