WebbTheoretical Assessment of Hinge-Type Models for Electron Donors in Reaction Centers of Photosystems I and II as Well as of Purple Bacteria Denis G. Artiukhiny1, Patrick … Webbhinge. a jointed device or flexible piece on which a door, gate, shutter, lid, or other attached part turns, swings, or moves. a natural anatomical joint at which motion …
Sci-Hub The Influence of Hinge Region Residue Glu-381 on …
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Discovery of a novel kinase hinge binder fragment by dynamic …
Webb24 nov. 2015 · A common feature of most kinase inhibitors is the presence of a hinge-binding moiety, 4 a group that is able to form hydrogen bonds to the cleft between N- and C-lobes of the kinase known as the hinge region. 4 Typically, a hinge-binding structure consists of a hetero-aromatic group containing hydrogen bond donors and/or acceptors … WebbThe hinge region in the ATP site can be used for designing potent inhibitors. In this review, we discuss some representative studies that will highlight the interactions of … Webb1 okt. 2015 · Depending on specific substitution patterns, scaffolds may demonstrate versatile binding capacities to interact with kinase hinge. Afforded by thousands of … ecotourism facilities in the philippines