http://www.xuankebio.com/Products-32255860.html Web25 de nov. de 2015 · 激活pkm2基因转录. 丙酮酸激酶的pkm1及pkm2亚型,是pkm2基因的选择性剪接产物。pkm2,而非pkm1,可改变癌细胞糖代谢以参与肿瘤发生,其机制尚不能通过pkm2已知的生化特性来解释。在这篇文章中,研究人员发现pkm2基因转录可被缺氧诱导因子1(hif-1)激活。
H3F3A 癌基因 - 癌症123
Web肿瘤相关巨噬细胞(TAM)浸润在肿瘤组织中,是肿瘤微环境中最多的免疫细胞,能通过促进基因不稳定、血管生成、纤维化、免疫抑制、侵袭和转移来促进肿瘤进展。在多种人类癌症中,大量的TAM与患者较短的总生存期相关… http://yxy.njucm.edu.cn/2024/1111/c2988a56737/page.htm earned owned paid shared
抑制蛋白结构域蛋白2抗体(ARRDC2)-上海晅科生物科技 ...
Web4 de abr. de 2024 · HIF3A methylation was found in the association between the HIF3A rs3826795 polymorphism and alanine aminotransferase among obese children. TIMP2 … WebHIF1A, HIF1B and HIF2A were significantly different in healthy aged tissues, and both HIF1A and HIF3A were positively correlated with aging. Beyond these transcription factor alterations, analysis of patterns of gene expression involved in hypoxic changes in tissues showed specific increases in metabolic pathway hypoxia-inducible genes, ... Web2016年,何川教授与陈建军教授在Cancer Cell发表研究,发现FTO在急性髓系白血病中通过调控m6A的水平,发挥癌基因的功能,促进白血病的发生发展【3】。 之后,陆续有研究表明FTO作为m6A去甲基化酶在多种生命过程中发挥作用【4,5,6】。 earned owned shared